Peptic ulcer is the discontinuity in the mucosa of GI tract due to excessive gastric acid secretion. Most common sites for peptic ulcers are stomach and duodenum.
Common causes of peptic ulcers are:
H pylori infection
NSAID use
Cigarette smoking
Hypersecretory conditions like gastrinoma
Hypercalcemia
Cirrhosis
Renal failure
Chronic obstructive pulmonary disease
Symptoms
Upper abdominal pain related to meals
Radiation of pain to the back
Vomiting of blood or black stool in case of bleeding from the ulcer
Severe pain abdomen in case of ulcer perforation
Diagnosis
Peptic ulcers are easily diagnosed on upper GI endoscopy
