Cholangiocarcinoma is the most common tumor of bile duct. Cholangiocarcinoma may involve the bile duct at liver hilum, lower CBD or intrahepatic biliary system. Hilar is the most common type of cholnagiocarcinoma
Rick factors are
Choledochal cyst
Clonorchis sinensis
Hepaticolithiasis
Primary sclerosing cholangitis
Biliary-enteric drainage procedures
Symptoms
Painless jaundice
Itching
Weight loss and anorexia
Fever and pain abdomen in the case of cholangitis
Diagnosis
Diagnosis is suspected when USG/CT/MRCP reveals obstruction of biliary system, and a mass around the CBD
For tissue diagnosis, EUS – FNA, ERCP-brushings, and spyglass with biopsy are available options
Treatment
Surgery is the best option for resectable tumors
For unresectable hilar cholangiocarcinoma, chemo-radiotherapy followed by liver transplantation is the new treatment strategy.
For advanced tumors, ERCP and stenting can be done for palliation of jaundice/itching and fever
